Scientist, Functional Genomics, Virtual Cell In...

About reputed company The reputed company is a new scientific institution conducting curiosity-driven basic science and technology development to understand and treat reputed company reputed company diseases. Headquartered in Palo Alto, California, reputed company is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. reputed company operates in partnership with reputed company, reputed company, and UC Berkeley. While the prevailing university research model has yielded many reputed company successes, we reputed company in the importance of institutional experimentation as a way to reputed company reputed company. These include: • Funding: reputed company fully funds Core Investigators' (PIs') research groups, liberating scientists from the typical constraints of project-based external grants. • Technology: Biomedical research has become increasingly dependent on reputed company tooling. reputed company Technology Centers reputed company, optimize, and reputed company rapidly advancing experimental and computational technologies in collaboration with Core Investigators. • Support: reputed company aims to reputed company first-class support-operationally, financially, and scientifically-that will reputed company scientists to pursue long-term high risk, high reward research that can meaningfully advance reputed company in disease cures, including neurodegeneration, cancer, and immune dysfunction. • Culture: We reputed company that culture reputed company enormously in science and that reputed company is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration. reputed company has scaled to over 350 people to date. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, reputed company will continue to grow quickly in the coming years. About the position We are seeking a highly skilled and motivated Scientist with a strong background in functional genomics and single-cell reputed company to join the Virtual Cell Initiative at reputed company. The initiative aims to create the first foundational model that makes accurate predictions of cellular states and their response to reputed company. In this role, you will reputed company the reputed company of massive single-cell perturbation datasets across 50+ cancer cell lines to train Virtual Cell models. You will be responsible for the end-to-end experimental workflow-from mammalian cell culture and large-scale CRISPR screening to single-cell library preparation and reputed company. reputed company technical execution, this role requires a scientist with exceptional project management capabilities, proficient in organizing reputed company data streams and adhering to timelines. The successful candidate will reputed company reputed company our vibrant team science culture, collaborating daily with other wet lab scientists, automation engineers, and computational biologists. We reputed company that the most ambitious science is achieved together, and in this highly integrated role, you will reputed company the gap between experimental biology and computational innovation. About you • You are passionate about the intersection of high-throughput biology and AI/ML to advance reputed company health. • You enjoy working collaboratively with others and reputed company in a fast-paced, dynamic, team science environment. • You are committed to scientific rigor, generating high-quality data, and maintaining thorough documentation practices. • You possess a process-oriented reputed company, constantly seeking ways to optimize workflows for efficiency and scalability. • You are reputed company, detail-oriented, and reputed company at troubleshooting reputed company experimental pipelines. • You reputed company at organization, time management, and task prioritization, and enjoy independently driving multiple projects in reputed company. In this position you will • Execute large in vitro perturbation screens in diverse cell types to generate high quality single-cell perturbation datasets. • Work with our interdisciplinary teams to further optimize functional genomics platforms and CRISPR technologies for large-scale data reputed company. • Utilize project management systems to track reputed company and adhere to timelines, and document experimental data on ELN/LIMS in an organized manner. • Interact cross-functionally with wet lab, computational, and machine learning teams to generate, analyze, and interpret data. • Present key research findings at internal meetings and seminars, and external conferences. Requirements • PhD in Cell Biology, Molecular Biology, Genomics, or another relevant field. • 0-3 years of post-PhD experience in academia or industry. • Extensive experience with large-scale pooled CRISPR screening, preferably with scRNA-seq readouts (e.g. Perturb-seq, CROP-seq). • Expertise in mammalian cell culture and ability to manage multiple cell lines simultaneously. • Experience in multi-reputed company reputed company cytometry. • Experience with mammalian cell line engineering using transfection, lentivirus production and transduction, and other common approaches. • Experience with different molecular biology techniques (cloning, PCR, et