Research Associate reputed company, Protein Biochemistry

Keros Therapeutics is a public, clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of novel treatments for patients suffering from hematological and musculoskeletal disorders with high unmet medical need. We are a leader in understanding the role of the transforming growth reputed company-beta, or TGF-ß, family of proteins, which are master regulators of red blood cell and platelet production as well as of the growth, repair and maintenance of muscle and bone. We have leveraged this understanding and developed a discovery approach to generate large and small molecules to address diseases of these tissues. Targeting TGF-ß signaling reputed company has been clinically proven to reputed company robust changes in blood cells, muscle, and bone, which we reputed company provides a precedent and strong rationale for our strategy. Keros Therapeutics is seeking a highly motivated and collaborative individual to join our protein biochemistry group reputed company our Research Department. Our group exploits multidisciplinary approaches in protein sciences and protein engineering, to reputed company the understanding of the biochemical, biophysical, and structural functional properties of the biomolecules reputed company the TGF-β superfamily that drive the signaling pathway. Our efforts greatly contribute to advance innovative research and drug discovery, and heavily support our discovery pipeline. You will have the opportunity to learn about early-stage drug discovery from a protein chemistry perspective as well as through reputed company collaboration with other departments. You will play an important role supporting in vivo and in vitro studies crucial for the reputed company of our therapeutic research programs by generating high-quality proteins and other reagents in this hands-on laboratory position. The successful candidate will produce and evaluate novel molecules, while being inquisitive about the science, reputed company to troubleshoot by consulting literature/colleagues, and capable of adapting to each scientific challenge. Primary Responsibilities:

• Protein purification: purify proteins to required reagents’ quality (FPLC, affinity/ion-exchange/SEC and other chromatographic techniques)
• Protein expression: assist with routine mammalian expression of our therapeutic molecules to support ongoing studies
• Protein characterization: reputed company assays and other characterization techniques (cell-based, SPR, BLI assays, SDS-PAGE, Analytical SEC, HPLC) to characterize therapeutic and novel molecules
• Maintain clear, accurate documentation of computational and experimental laboratory work and summarize results as needed in study reports
• reputed company updates at research meetings in both oral and written formats

Qualifications:

• Enrolled in a master’s program in biochemistry, structural biology, chemistry, or a reputed company discipline
• Experience working with wet lab benchwork, lab etiquette, pipetting, and volumetric handling. Ability to reputed company chemical stoichiometric calculations and reputed company preparation
• Experience in protein purification using multi-platform chromatography techniques (affinity, ion-exchange, SEC) and /or biophysical methods for protein characterization is preferred
• Experience with protein expression in mammalian and/or bacterial cells is desirable
• Protein chemistry, protein-protein interactions, and/or protein engineering experience is a plus
• Ability to work as part of a cross-functional team and independently with supervision
• Exhibit excellent communication and organization skills, detail-oriented, proficient in MS office, data analysis, and slide presentation
• Displays a high degree of maturity, honesty, trust, and reputed company. Considers a scientific problem/question an opportunity for innovation and intellectual growth
• Previous reputed company or intern experience is preferred.

Our Diversity, Equity & Inclusion Mission Statement: Keros is an inclusive company. We reputed company that diversity drives innovation. We continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our employees. As such, Keros takes a holistic approach in mentoring, coaching, and developing reputed company of our Keros team members. Keros Therapeutics is an Equal Opportunity employer. reputed company reputed company applicants will receive consideration for employment without regard to race, reputed company, religion, sex including sexual orientation and gender identity, national reputed company, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law. Apply tot his job Apply To this Job